Forum Replies Created
Wendy
These drugs are very hard on their tummies. If it is a one-off, don’t worry. Obviously, if it carries on, you need to see the vet immediately as Frank cannot afford to throw up his medications & you mustn’t let him get dehydrated either. There are medications such as Cerenia or metoclopramide which can help with nausea/vomiting. It is not unusual for high (loading) dose cyclosporine to make them throw up. This resolves when you lower the dose. Have good read of this please:
https://www.secondchanceaihadogs.com/AIHA_Terms/cyclosporine/
Paragraph 5 explains about nausea, vomiting & diarrhoea.
Please don’t worry too much as this is easily remedied – I think this has happened to most of us – and yes, of course we worried too!
Love Sheena x
Hi Linda
I bet you’ll never miss those signs ever again! Don’t feel bad, please, these things happen & it was just terrible luck that this infection was so nasty.Yes, we need to get our thinking caps on for something to prevent this happening again. I would still run anything we come up with by Jean Dodds though – you never know what might not be good for our special IMHA pups & kitties.
Incontinence sheets from the pharmacy sound like a great idea – everyone can have a peaceful night. I can’t sleep properly without Worzel right next to me any more – spoilt or what! When it’s hot, Phil goes in another bedroom as he can’t stand lying next to Mr Hot Water Bottle – good job he’s so understanding. Mind you, he also says I snore …. I don’t believe that for a minute though!
When we first had Worzel, he was on antibiotics for a bladder infection for about two months – he had loads of wee accidents, but he couldn’t help it. My poor old Mum’s incontinence bed sheets & chair pads came in quite handy!
Love & hugs from us all
Sheena & the boys xxxxx
Hi Wendy
I did tell you I thought it was Evans Syndrome early on, but I bet you were so overwhelmed that you didn’t really take everything in – quite understandable (see my post on page 5 from the 18th July) – don’t worry – the treatment is the same, although sometimes Vincristine is used in addition to cyclosporine in Dr Dodds protocol. We have had quite a few cases on here, as everyone has mentioned & some have been given Vincristine too. Hopefully, Frank will continue to respond to the cyclosporine well & it won’t be necessary to add anything else though.
I’m so happy his PCV has gone up – that’s really cheerful news. You just need to keep an eye on his platelets though. The last blood tests I saw, they weren’t too bad – nowhere near being dangerously low.
How lovely that someone helped you with the vets bill – there really are some great people around!
So things are looking better all the time – fingers crossed for Frank to carry on going up & up.
Love & hugs
Sheena & the boys xxxxx
Hi Wendy
This is wonderful news! More happy dancing!
Yes – we have seen a few cases of Evan’s Syndrome here. My understanding is that treatment is the same, so lets hope Frank’s platelets will soon start to come up too. Do you know if there has been any change in the platelets yet? We had a lady called Ruth and her dog Nula, who recovered from Evans. If you search back in the forum, you’ll find her story.
That’s so lovely that someone paid for Frank’s visit. There are some really decent people in this world. Sometimes I feel as though I’m losing faith in humanity, and when I come to this site and talk with people who love animals, it’s instantly restored. I don’t know who paid for Frank, but whoever it was is awesome, and obviously thinks a lot of you and Frank.
Things are going in the right direction. Big hugs for you and Frank,
Mary and Mable x
Hi Linda
Sorry should have posted on the site as well as an e-mail – but I do agree with Brigitte – the pred won’t help these issues as their back ends tend to get weak – why not bladder muscles too! And of course they are drinking loads & peeing loads too.
I wrote (agreeing with Mary actually) – “Linda – this incontinence is due to the infection inflaming her bladder etc. & I wouldn’t blame it on the immunosuppressants myself. My little Millie had a terrible UTI – pus coming out & blood – it took her a while to stop having little accidents even after we stopped the antibiotics – I think it was a couple of months – she was such a clean little soul & she was really upset – it’s horrible for them. I was considering using propalin syrup (but that’s not an option for you with Sadie’s IMHA) when all of a sudden she got better! I know you don’t give a damn about the accidents – you’re just worried about her well-being.
I think in the circumstances you should get precise weaning advice from Dr Dodds. I personally think she’d get you to lower the cyclo to a normal dose (like Dewey) THEN start the pred slowly, but please get her to tell you exactly what to do as we do not want anything to rock the boat!”
Love & hugs
Sheena & the boys xxx
Ps I do remember someone using doggy diapers but who was it? Can’t remember – can someone help us with this? I would never stop Worzel sleeping on the bed with us even if he had accidents, so would try the diaper option if he didn’t mind. We love them too much to worry about minor things like a stray wee-wee here & there!
Hiya Pam
Goodness, this is hard getting medications into your poor Emily – more difficult than with doggies for sure. My very old friend Theresa (by whom I met Mary) wraps her “difficult ones” in a towel to give meds – it avoids ER visits! I can appreciate that it is not ideal to say the least, but maybe worth a try????? Mary – your ideas are really worth a go – good luck Pam – very frustrating for you. Emily sounds like a real sweetie pie & we always feel bad showing this stuff down their necks – they don’t understand we ARE trying to get them better! Is there any way you could restrict her to a certain area, so that she can’t sneak off & hide? Or even a large cage?
From what you have said, my suspicions still go with an infection – it will take someone far more more clever than me by far to be certain. At the end of the day though, why not go with treating an infection? What’s to lose? Nothing actually. That was what we did – basically, doxycycline will kill of just about anything & that was what we opted for with Worzel. A course of antibiotics may prove/disprove our theory & would do no real harm. But he needed that immuno-suppressant as bone marrow failure was obvious. Would you be able to dissolve & syringe an antibiotic, rather than use a pill? If not, an injection surely is available. It does worry me that pred alone may not be the right thing to do BUT because she is nowhere near emergency levels, you do have time to play with, so no need to panic.
I am sorry the vets have this strange illusion that IMHA is regenerative – we have had many, many cases classed as non-regenerative – hence the explanation on the first page of the website. The level of regeneration for Emily is no where near high enough BUT she is producing some baby red cells – not enough admittedly but a bit better than the big fat ZERO Worzel was producing – maybe this could be why she is holding her level? Or the pred is preventing over-destruction of the cells? Or as Mary rightly says, she has reverted to producing cells in organs other than the bone marrow, which is keeping her going. The body is amazing & will always try to heal itself somehow – by reverting to embryonic stage for blood cell production in certain circumstances, as with Patrice’s Chance.
I am so sorry we can’t give you a more precise answer – that really is internal medicine specialist territory, plus infectious disease expert investigation. Could there be a second factor that sent Emily over the edge, such as a recent vaccination? Or a flea/tick/heartworm treatment? Worth asking you if there is anything else you can think of – even eating something she shouldn’t have?
Trying to get to the root of the problem is not easy – Pam, I really feel for you & Emily. At least she sounds pretty feisty in herself – that’s always good news – even if she is picky with food, at least she will eat some things!
Love Sheena & the boys xxxxx
Link moved as text was messed up
http://www.avsg.net/files/7614/0511/6749/ImmuneMediatedHemolyticAnemiaHeatherMineoDVMDACVECC.pdf