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- sassy is relapsing.
Hi everyone. Sorry, I haven’t had the energy to make a post as I’ve barely been getting any sleep. It has been a very rough time. Sassy is still with us but we are teetering.
I tried more than once to call dr. dodds, and so did my vet. she is out of the country, and her assistant never got back to us.
Sassy had a transfusion that she ate through in less than 24hrs. Her whites also went up to 30/ and… her bun? I think, the kidney value. it was high and we were worried of renal failure. She was at 14 PCV before and only at 16 the next day, with platelets at 40 (from zero). So, we were already preparing for another.
I mentioned the IVIg in an earlier post and that it was out of the question because the ONLY place was nearly a 4 hour drive and she was not strong enough to do it. Well, I left Sassy for her second transfusion with little hope and got a very unexpected call. My vet called and told me the specialist was willing to call our hospital, the human one, and release the IVIg to her and explain the procedure. At that point I couldn’t say no and I gave her the money to go buy it from the hospital. So she had half a transfusion last night and a slow drip treatment of IVIg. She did well through the night, and ate a grilled cheese this morning. We did not test her PCV last night because we were going to come straight in at 8:30 and finish it, and wanted her to keep every drop of blood she had. She was with the vet until around 10 last night, and it was a blessing she came home and was with all of us at midnight (New Years). We all hugged and kissed sassy for New Years and everyone was crying.
It was a very long night but uneventful. sassy got some deep sleep. I made myself a grilled cheese around 6am and she wanted it from me so I fed it to her (it was at least whole wheat bread and fat free cheese). we left at 8 and she was there until around 11. after finishing the second half, her PCV is only at around 15.8%. She’s just come home. However we’ve had some encouraging signs:
-Whites have gone down to 24
-the kidney value returned to normal
-bilirubin went from 4.8% to 3.3%
-and the big encouragement was platelets went to 150.
-she’s doing baby stretches when laying down and readjusting herself. before she would give up trying to get her foot in the right position for instance and we’d have to move and position her entire body for her.
-she wants to be pet
We are praying so hard she is stabilizing at this number. If we can just stop the rapid destruction. The rate is insane.
I had the vet start baby aspirin and sulfarlcate (spelling?). She has diarrhea that is pure water. I have a tube of tarry looking medicine to squirt in her mouth to help that.
All we can do at this point, is hope the IVIg works and try to buy her the time. Hemopet is OUT of packed red cells until the 7th. No one in the state has it, either. That is what we wanted to order to have on hand, but our only option is more whole blood. My vet called an emergency clinic about 1.5 hours away (open nights and holidays), and they are willing to sell her blood instead of force us to bring sassy there. so if she starts crashing that is our backup plan/only option.
I’ve put out a plea on my Facebook to ask for donations…
I’m doing everything I can but that IVIg was 2,000 alone. that isn’t counting the 2 transfusions, pills, test, and after hour visits.
I’m sorry, I do not have her test results. I’ve gotten so little sleep and have forgotten to get copies every single time. Angry at myself. I know today she told me her protein was low.
It’s difficult finding anything she wants to eat right now, and she’s very very thirsty.
Alyssa
Don’t even think about getting angry with yourself about the tests – it doesn’t matter. What’s really important is that you are with Sassy & my goodness you are doing an AWESOME job of getting her everything she needs, together with your vet.
I’m so upset to hear Dr Dodds is away & no-one is around to help you – persevere – try e-mailing her & phoning again. Once, she got back to me even though she was in the middle east. Rotten luck on the timing for you & so stressful that no packed reds are available.
Do you know anyone with a greyhound or other sight hound that would be willing to give blood? They have very high PCVs & as you know that is where Hemopet blood products come from. They would have to be properly cross matched & be a healthy disease free dog – just an idea as a fallback in case of an emergency. My Ollie would gladly give you some if we weren’t so damn far away.
You’ve been through the extreme thirst before I’m sure – I had a big water bowl in the bedroom for Worzel at night as he was desperate for a drink. Thank you for the update – we are all hoping, praying, crossing everything, plus anything we can think of to “will” Sassy to improve. Things do sound much, much better on her results that you mentioned – that is such positive news, Alyssa.
Please try & get some sleep – I bet you are cuddled up with her as often as possible – sneak a power nap!
Sending you masses of love, hope & big hugs
Sheena, Worzel & Ollie xxxx
Alyssa,
Your excellent report sounds quite good in fact and that she is responding to you is super. There are improvements to be happy about. Her body is also working very hard to recover. Sometimes I am amazed at the great will to live and how dogs will recover from the very worst things. I would not put it past Sassy to recover due to her very strong will to live.
I have a paper about the use of human IVIG on the website you can read, the results of a study, performed on dogs to determine if the use of human IV immunoglobulin is of benefit to dogs with severe immune-mediated thrombocytopenia.
Go to this page
https://www.secondchanceaihadogs.com/medication-resources/#mg
and click on the picture of this pdf: “Treatment of Canine IMT with Human IVIG.” It will open the pdf in a window where you can read the paper, click on the arrow to enlarge it to full screen. Once in the full screen you can print it or save it as you wish. Probably the section titled Discussion will be most interesting to you.
Here is a summary of the results.
“Conclusions and clinical importance:
Human IVIG was well tolerated and appeared to be associated with rapid platelet count recovery and amelioration of clinical signs in most dogs with IMT.”
While this is a small study, it is an important one. Canine IVIG products were actually developed in the past but the project was abandoned due to the overwhelming expense of the treatment. Researching the use of the human product on dogs was critical to determine if they would develop antigens to the human proteins. This study seems to indicate that the risk is low and the treatment is effective.
This was a critical part of her treatment. I know the expense is overwhelming, but I believe your vet is struggling to make all of this work for you. Lean on him/her for your strength and support.
my best
patrice
Hello
Alyssa,
You are a Superhero! You really do all you can for Sassy, now it is basically up to her. She sounds like such a fighter, I know she is giving it her all. There is already some small improvement and I am crossing fingers and toes Sassy will keep fighting.
Make sure you are not getting run down. I know this is not just physically but also mentally very draining. I know you have a very strong shoulder in your boyfriend, I am so glad for that.
Best wishes,
Brigitte
Alyssa if you have any emails from Dr Dodds send her a response and shell get it. She usually responds very quickly. She observes the Sabbath so you wont hear in that time.
Tou are amazing and make sure you tell Sassy that. Tell her to keep fighting. And make sure you make extra toasties so you get to eat one too!!!
Love Vally
Sassys platelets have shot up to over 300… her bilirubin is down to 1.2% (it dropped down 2% overnight), but her PCV has continued to drop and she is at 12%. We are unsure what to do. It’s possible she rejected the transfusion and the platelets were a response to the IVIg. I’m at a loss guys :(
Agree with Vally – contact marked urgent Dr Dodds. Good news on the platelets – can you source any packed red cells from anywhere else?
Found this
http://www.vetbloodbank.com/price-list/
I can only suggest you keep her going with some small red cell transfusions until Dr Dodds is around.
Her PCV is not in danger levels & platelets are better – these are both good things – please be encouraged by this. Remember red cells take much longer to form than platelets ( platelet levels come up in a matter of days). Do you havs a reticulocyte figure? That would tell us if Sassy is making new baby reds.
Sheena xxxxxxx