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The vet told me yesterday that he’s got steve on the pred dosage that he came in on. I don’t know who initiated it in the beginning, the emergency clinic he was at on Saturday and Sunday or our general vet who has now said she feels she’s out of her depth with this. I know it’s 80mg only because when our general vet sent him home on Tuesday she gave me a med list with instructions and it said 2 20mg every 12 hours. I’ll speak to him the internist about it as soon as he calls today.
I don’t know if it is helpful at all, but I emailed STeve’s results as of Monday, 6/2 when he was diagnosed with primary IMHA. After these results, he was started on the 40mg Pred BID. I’m still trying to get in touch with the internist to talk about the prednisone dosage, as well as ask again for the most recent lab results.
I’m including the lab results here also (from Monday, 6/2):
RBC – 1.40 M/uL
HCT – machine got 10.3%; manual got 21%
HGB: 7.1 g/dL
MCV: 73.6 fL
MCH: 51.0 pg
RDW: 18.3%
% RETIC: 10.8%
RETIC: 151.3 K/uL
WBC: 21.67 K/uL
% NEU: 83.0%
% LYM: 8.6%
%MONO: 6.1%
%EOS: 1.7%
%BASO: 0.6%
NEU: 17.98 K/uL
LYM: 1.87 K/uL
MONO: 1.32 K/uL
EOS: 0.38 K/uL
BASO: 0.13 K/uL
PLT: 741 K/uL
MPV: 11.6 fL
PDW: 20.6%
PCT: 0.86%
Thank you all so much!
Hope
Hi Hope
Just want to welcome you to the site and to say how sorry I am you are going through this. I’m the cat owner here, and my cat Molly had a rare form of AIHA in her bone marrow late last year. We’ve all been through this and understand what a difficult time it is. I’m in a mad hurry right now but promise to write more later.
I hope you manage to get Steve home tomorrow
Mary and Mable x
Thanks so much! I read Molly’s story last night actually — it’s so good to have people out there who know what this is like. <3
Hi Hope, I’m new here too. I just wanted to say welcome and I’m so sorry too that you’re going through this, it’s just awful and so scary. I’ve been so exhausted and overwhelmed. It really seems like you’re so on top of everything. You can drop a note to Dr. Dodds and she will get back to you, that’s what I did. I also had Ashki’s thyroid tested at her lab as one part of the trigger can be hypothyroidism. Her lab has breed specific ranges, and can interpret with all the drugs as well. Sure enough, Ashki was hypothyroid and so the holistic vet that Ash is seeing started him on thyroid therapy as the internist did not want to. These doctors can be frustrating — although in my case I know the internist cares very much about Ashki and I think that is part of the control issue there. Right now I’m willing to work with it.
When I brought Ashki home I was so scared and worried, I was at the vets often just to have his PCV checked as I was so scared. Another reason I like the internist is their practice is an emergency practice as well so I can take Ash there anytime and have him checked (which I have! nights and weekends :) ).
I just realized as I was reading your thread that Ashki was on 80 mg pred (40 twice daily) during the first week of treatment (he weighed 66 pounds at the time). I’m wondering if it’s a new approach? Dr. Dodds says to give 1 mg/lb, which is what he’s on now and has been since week 2.
Anyway, just wanted to say hi and I’m thinking of you and your husband and of course Steve and sending you hugs and sending Steve healing vibes.
Tamara and Ashki
Hi Hope
I’ve just had a good read through your post and again, am sorry to hear that Steve has this horrid illness. I also remember waiting endlessly for phone updates and I know it’s hard. I guess they are just very busy, but it’s difficult to be patient waiting for news.
I was also told not to read up on IMHA on the internet by Molly’s specialists. For me, it was impossible not to. I wanted to learn as much as I could. In some respects, your internist is right, as you do need to be careful about sources of information. We are not vets, but we have been through this and have learnt a lot in the process. The people here are very well informed and will not tell you anything unless they have absolute confidence in it. Even then, if we suggest something and you don’t agree, that’s absolutely fine and we will respect your decision. I think it’s just good to be able to make informed decisions. You are well within your rights to ask about Steve’s medication, and the rationale for selecting mycophenolate. I’m sure your vet has a reason for choosing this drug, but it would be helpful if he could explain this to you. I really don’t know anything about this drug, but I would be (pleasantly) surprised if any long acting immunosuppressant was to take effect in 24 hours. I’m certainly not disagreeing with your vet as I don’t know, but I am surprised as most of these types of drugs take days/weeks to kick in.
Not sure what others think, but I would also ask again about antibiotics, if Steve still has any hint of a temperature or raised white cell count. Doxycycline is widely used in IMHA cases, although I don’t know what it interacts with, so it may not be suitable for Steve.
The PCV fluctuations are a bit confusing I admit. I agree with your vet that small fluctuations are normal and to be expected. As you can see by the blood results you posted, the manual vs. machine PCV can have markedly different results, and this was something that came up recently for another user here. Other factors such as blood clots in the sample can affect the results.
Some vets sadly do get a bit defensive, and I suppose it’s possible that your vet thinks you don’t trust what he’s doing. I think it’s fine to explain that you know he wants what’s best for Steve, but that you want to know everything that’s happening. He is your dog, you are paying for his treatment, and therefore you have every right to that information. It is a process of working together for the best outcome. I respect your general vet for saying she feels out of her depth. It is much better that she is honest about this rather than trying to treat Steve without the correct knowledge. My local vet had never seen a case of the disease Molly had. IMHA cases are rare and a lot of primary care vets do not know a lot about the treatment of it.
I’m not 100% sure about the prenisolone dose but it sounds high to me, and based on what the others have said, I’d really recommend you talk to the vet again about this. They should have a protocol for the doses they give. If they do not have a treatment protocol (which it sounds like they do), they should at least have a reason for selecting a particular dose.
I would also recommend you contact Dr Dodds, and perhaps your vet would feel more comfortable with this? She is a wonderful source of knowledge, an expert in this disease, and is very good about getting back to you.
Please don’t beat yourself up about the Zinc cream. You cannot possibly know everything, and as has already been said, I think we’ve all found that we’ve done things we wish we hadn’t. I’ve lost count of the number of calls to our vets after one of the cats had eaten various items they shouldn’t have! In fact, there is a cat treat here in the UK which is Zinc based. Crazy huh? But without knowing about IMHA, I’d not have known to avoid it. You have nothing to feel guilty for at all.
Anyway, fingers crossed that Steve is doing well today and will be able to come home and have a big cuddle. Keep your chin up. It’s a long, hard battle but Steve is lucky to have you and your husband to look after him.
Mary & Mable x
- This reply was modified 10 years, 6 months ago by admin.
Hey all!
Thank you so much for being here for me again — y’all have been so amazing!
Steve came home this morning… the doctor called and said that his PCV was at 27% (5:00 am) so he feels he is “definitely stable.” He’s been bouncing around between 20-27% since about Wednesday . Is that something that y’all would feel comfortable with?
The zinc test came back negative, and so far the urine culture looks clear too. He said that his urine since Tuesday night-Wednesday morning has been clear or at least hemaocrit and bilirubin free. He feels like the blood might have something to do with the urate stones in his bladder? Does that seem reasonable?
The meds he was discharged on are as follows:
Prednisone – 50mg/day (25mg BID) –> I spoke with him about the high dosage yesterday and he said he was originally going to taper him down on Monday but he went ahead and did it today since I was concerned.
MMF – 375 mg/day (250mg AM, 125mg PM) –> he said he thinks this works better than some of the other ones that take a week or more to show effect? And that he’s seen weird side effects with some of the others like Cyclosporine (fungal infections that are difficult and expensive to treat)
Famotidine – 5 mg BID
Lovenox – 0.22mL TID via injection (horrifying!)
Aspirin – 1/8 81mg tablet BID
We still haven’t gotten him to give us lab results … I don’t know what to do about that.
Could anyone offer any insight? I’m sorry — I know it’s difficult without his full workup but any advice would be appreciated. How does the current prescription regiment look?
Also a few questions…
1) does anyone have Dr. Dodd’s email info? Or what is the best way to get in touch with her?
2) Since his PCV is fluctuating a lot even in a single day, would/could that indicate clotting?
3) just since he’s been home he’s been urinating SOOOO much! Granted he’s drinking up a storm but he is peeing at least every 1 hour and 45 minutes and usually it’s two times each break. He even peed on my feet once when I didn’t know he had to go and then a tiny bit in his sleep. I know this is a side effect of the pred but is that normal?! It’s been light yellow/almost clear each time but still…
Thanks everyone!
Hope
Hi Hope, I can’t answer very many of your questions, but I can answer a couple. Dr. Dodds’ website is http://www.hemopet.org and the email address is (deleted). I just emailed that address with the subject line 3yo Golden with IMHA and asked for help and she sent me a bunch of information.
If you really like your vet who felt out of her depth, I wonder if she would feel comfortable managing the case with Dr. Dodds’ guidance? You can purchase a consult on the Hemopet website under forms — there’s one for a consult there.
When I brought Ashki home he was peeing like Steve is peeing — as often and as much. It has decreased a bit as his dosage was reduced and I think Ash has adjusted a bit — I would say about half the time he wakes me up once or twice a night now to go out.
Thinking of you all and sending you hugs —
Tamara and Ashki
- This reply was modified 10 years, 6 months ago by admin.