Rouleaux – not strictly a miss-shapen cell (poikilocyte), but relevant as you may see them reported on your pet’s blood smear. Red cells almost “form a line” & look like a stack of coins because the cells are aggregating or sticking together – seen in anemia, infections, inflammatory diseases, diabetes mellitus, multiple myeloma, cancers & macroglobulinaemia (seen in lymphoplasmacytic lymphoma), also seen when plasma protein concentration is increased & when erythroid sedimentation rate is high.
See also poikilocytes
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