Famotidine

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Famotidine (brand name Pepcid) is used to treat oesophageal & gastro-intestinal ulcers, gastritis (inflammation of the stomach), oesophagitis, acid reflux & for dogs with mast cell tumours. Famotidine is very useful during AIHA treatment to prevent/heal ulceration & inflammation to the GI Tract which can be caused by many of the drugs (e.g. immuno-suppressants, antibiotics, ultra low-dose aspirin etc). ALWAYS ask your vet before giving Famotidine to you dog.

Famotidine should be given with caution to dogs with heart, liver or kidney disease, pregnant females, or if the dog has any allergy to the ingredients, although it is often use to prevent ulcers in dogs with kidney failure. ASK YOUR VET.

Famotidine is an anti-histamine which works by blocking H2 receptors, which reduces the amount of stomach acid being produced.

Dosage: Approximately 0.25 to 0.5 mg per pound (0.5 to 1.0 mg/kg) every 12 to 24 hours, given APART from other medications as it may prevent their proper absorption. 2 hours before or 2 hours after other medications is the recommended way. It should not be given with food as it’s effectiveness would be reduced.

Possible interactions with other drugs include: Digoxin, Ketoconazole, Metoclopramide, Antacids, Sucralfate. Famotidine can cause a further reduction in WBC (white blood cell count) if given with azathioprine. ALWAYS ask your vet for advice.